The drug for coronavirus infection should be taken under the control of the doctor, after blood tests and ECG. It is toxic to heart, contraindicated in case of arrhythmia, pregnancy, renal and liver failure. Chloroquine is not recommended for prevention, and its analogs are used for doctors after contact with infected. Independent reception is dangerous with its complications, as it may cause convulsions, loss of vision, deterioration of the brain, and cardiovascular circulation.
Causes of Chloroquine selection for coronavirus
Chloroquine is used for coronavirus, or rather, its complications – viral pneumonia with cytokine storm syndrome. It is the figurative name of the fatal reaction of the immune system in the heart of pneumonia.
The inflammatory process caused by the virus attracts many lymphocytes into the pulmonary tissue. They are destroyed and emit cytokines – small protein molecules, signaling dangers, and attracting even more immune cells. This leads to the destruction of the lungs and the spread of defeat to other internal organs.
Chloroquine can interrupt this reaction, as suppresses the immune system. The interest in it arose when the used anti-inflammatory agents (hormones, non-steroid drugs) caused rapid reproduction of coronavirus. They were banned then.
Chloroquine was effective for coronavirus, while there is a confirmed anti-virus action only outside the body. Before this, the drug was used for malaria, and later it was found that it helped for the autoimmune diseases. They are characterized by the reaction of the immune system (antibodies) on their own tissues. It is the ability to suppress immunity and was necessary for a patient with coronavirus with cytokine storm syndrome.
The media hastened to say that the remedy for the new infection was found, and Donald Trump said that Chloroquine had caused good foreboding. It is partly true, but it is too early to declare the ability to stop the epidemic. The same applies to a large group of other anti-virus drugs (Favipiravir, Remesivir, Ribavirin). They helped cure patients in China and Western Europe, but it took too little time for the necessary research.
Contraindications and possible complications of Chloroquine
Chlorophosphate is not used for coronavirus if there are contraindications:
renal, liver failure;
bone marrow defeat with the oppression of blood circulation;
low level of leukocytes;
The drug is not harmless and can cause a number of complications:
allergic reactions – inflammation and itching, sprinkling, increased sensitivity to sunlight;
sickness in the stomach, nausea, vomiting;
mental disorders, headache, dizziness, insomnia;
convulsive twitch muscles, seizure attack;
heart muscle defeat with changes on ECG;
a drop of blood pressure;
deterioration of vision – the dimness of the cornea, vascular changes on the eye bottom;
the ringing in ears, violation of brain circulation, especially after 65 years.
How is Chloroquine used in coronavirus treatment? Does it really help?
Chloroquine doesn’t help in the treatment of coronavirus, but the doctor should accurately determine the time for its purpose, as the decrease of immune reaction is not desirable. Therefore, therapy is always carried out in the hospital when you can constantly monitor the condition of lungs and blood tests.
An important condition of application is regular ECG. It should be taken at the start of the therapy and then once in 5 days. The dosage of Chloroquine for coronavirus is 500 mg twice a day for a week..